Home / GATE 2017-2018 / GATE Biotechnology :: Practice Test Paper 1

GATE 2017-2018 :: GATE Biotechnology

  1. Synteny refers to
  2. A.
    gene duplication from a common ancestor
    B.
    a tree representation of related sequences
    C.
    the extent of similarity between two sequences
    D.
    local conservation of gene order

  3. While searching a database for similar sequences, E value does NOT depend on the
  4. A.
    sequence length
    B.
    number of sequences in the database
    C.
    scoring system
    D.
    probability from a normal distribution

  5. In transmission electron microscopy, electron opacity is greatly enhanced by treating the specimen with
  6. A.
    ferrous ammonium sulfate
    B.
    uranium acetate
    C.
    sodium chloride
    D.
    basic fuchsin

  7. The molarity of water in a water : ethanol mixture (15 : 85, v/v) is approximately
  8. A.
    0.85
    B.
    5.55
    C.
    8.5
    D.
    55.5

  9. The helix content of a protein can be determined using
  10. A.
    an infrared spectrometer
    B.
    a fluorescence spectrometer
    C.
    a circular dichroism spectrometer
    D.
    a UV-Visible spectrophotometer

  11. Which one of the following DNA sequences carries an invert repeat?
  12. A.
    ATGAGCCCCGAGTA 
    TACTCGGGGCTCAT
    B.
    ATGAGCCGGCTCTA 
    TACTCGGCCGAGAT
    C.
    ATGAGCCGAGCCTA 
    ACTCGGCTCGGAT
    D.
    ATGAGCCTATGGTA 
    TACTCGGATACCAT

  13. In zinc finger proteins, the amino acid residues that coordinate zinc are
  14. A.
    Cys and His
    B.
    Asp and Glu
    C.
    Arg and Lys
    D.
    Asp and Arg

  15. Match the entries in Group I with those in Group II.
    Group I                  Group II
    P. MTT                 1. Dihydrofolate reductase
    Q. Annexin V       2. Succinate dehydrogenase
    R. Methotrexate  3. Microtubules
    S. Taxol                 4. Phosphatidylserine
  16. A.
    P-3, Q-1, R-4, S-2
    B.
    P-2, Q-4, R-1, S-3
    C.
    P-2, Q-3, R-4, S-1
    D.
    P-4, Q-2, R-1, S-3

  17. In an exponentially growing batch culture of Saccharomyces cerevisiae, the cell density is 20 gl-1 (DCW), the specific growth rate (μ) is 0.4 h-1 and substrate uptake rate (v) is 16 gl-1h-1. The cell yield coefficient Yx/s will be
  18. A.
    0.32
    B.
    0.64
    C.
    0.80
    D.
    0.50

  19. A single base pair of DNA weighs 1.1 * 10-21 grams. How many picomoles of a plasmid vector of length 2750 bp are contained in 1 μg of purified DNA?
  20. A.
    0.30
    B.
    0.55
    C.
    0.25
    D.
    0.91